Format

Send to:

Choose Destination
See comment in PubMed Commons below
Pediatr Dermatol. 2008 May-Jun;25(3):403-4. doi: 10.1111/j.1525-1470.2008.00699.x.

The use of naltrexone in the management of severe generalized pruritus in biliary atresia: report of a case.

Author information

  • 1Department of Dermatology, Loma Linda University Medical Center, Loma Linda, California, USA.

Abstract

Generalized pruritus secondary to cholestasis is a difficult dermatologic condition to treat. We present a case of a 17-month-old child with congenital biliary atresia with generalized pruritus refractory to treatment with oral antihistamines, topical steroids, cholestyramine, and rifampin but improved remarkably with the addition of naltrexone. Naltrexone is a well-tolerated medication with little adverse effects. We believe that naltrexone may be an effective adjuvant treatment in the management of cholestatic pruritus in the pediatric population.

PMID:
18577062
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Write to the Help Desk