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Virus Genes. 2008 Oct;37(2):168-76. doi: 10.1007/s11262-008-0251-z. Epub 2008 Jun 24.

Phylogenetic analysis of swine influenza viruses recently isolated in Korea.

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  • 1Research Unit, Green Cross Veterinary Products, 227-5, Kugal-dong, Kiheung-gu, Yongin, 449-903, Republic of Korea.

Abstract

Several influenza A viral subtypes were isolated from pigs during a severe outbreak of respiratory disease in Korea during 2005 and 2006. They included a classical swine H1N1 subtype, two swine-human-avian triple-recombinant H1N2 subtypes, and a swine-human-avian triple-recombinant H3N2 subtype. In the current study, genetic characterization to determine the probable origin of these recent isolates was carried out for the first time. Phylogenetic analysis indicated that all the recent Korean isolates of H1N1, H1N2, and H3N2 influenza are closely related to viruses from the United States. Serologic and genetic analysis indicated that the Korean H1N2 viral subtypes were introduced directly from the United States, and did not arise from recombination between Korean H1N1 and H3N2. We suggest that the H1N1, H1N2, and H3N2 viral subtypes that were isolated from the Korean swine population originated in North America, and that these viruses are currently circulating in the Korean swine population.

PMID:
18574682
[PubMed - indexed for MEDLINE]
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