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J Cosmet Laser Ther. 2008 Jun;10(2):93-102. doi: 10.1080/14764170701883660.

The five D's of botulinum toxin: doses, dilution, diffusion, duration and dogma.

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  • 1The Mount Sinai Medical Center, Dermatology, New York, NY, USA.


The purpose of this review is to update cosmetic dermatologists and surgeons on the latest information about botulinum toxin injections for the treatment of the face and neck and to provide a practical guide to effective and safe technique. We review indications, recommended doses and dilutions, storage recommendations and injection techniques.

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