Electromagn Biol Med. 2008;27(2):147-54.

Upregulation of specific mRNA levels in rat brain after cell phone exposure.

Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HS.

Source

Department of Plastic and Reconstructive Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. jyan@mcw.edu

Abstract

Adult Sprague-Dawley rats were exposed to regular cell phones for 6 h per day for 126 days (18 weeks). RT-PCR was used to investigate the changes in levels of mRNA synthesis of several injury-associated proteins. Calcium ATPase, Neural Cell Adhesion Molecule, Neural Growth Factor, and Vascular Endothelial Growth Factor were evaluated. The results showed statistically significant mRNA up-regulation of these proteins in the brains of rats exposed to cell phone radiation. These results indicate that relative chronic exposure to cell phone microwave radiation may result in cumulative injuries that could eventually lead to clinically significant neurological damage.

PMID:: 18568932; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Qualitative effect on mRNAs of injury-associated proteins by cell phone like radiation in rat facial nerves. [Electromagn Biol Med. 2009]
Qualitative effect on mRNAs of injury-associated proteins by cell phone like radiation in rat facial nerves.
Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HS. Electromagn Biol Med. 2009; 28(4):383-90.
1439 MHz pulsed TDMA fields affect performance of rats in a T-maze task only when body temperature is elevated. [Bioelectromagnetics. 2003]
1439 MHz pulsed TDMA fields affect performance of rats in a T-maze task only when body temperature is elevated.
Yamaguchi H, Tsurita G, Ueno S, Watanabe S, Wake K, Taki M, Nagawa H. Bioelectromagnetics. 2003 May; 24(4):223-30.
Melatonin reduces oxidative stress induced by chronic exposure of microwave radiation from mobile phones in rat brain. [J Radiat Res. 2008]
Melatonin reduces oxidative stress induced by chronic exposure of microwave radiation from mobile phones in rat brain.
Sokolovic D, Djindjic B, Nikolic J, Bjelakovic G, Pavlovic D, Kocic G, Krstic D, Cvetkovic T, Pavlovic V. J Radiat Res. 2008 Nov; 49(6):579-86. Epub 2008 Sep 29.
Review [Effects of the microwave radiation from the cellular phones on humans and animals]. [Ross Fiziol Zh Im I M Sechenov...]
Review [Effects of the microwave radiation from the cellular phones on humans and animals].
Galeev AL. Ross Fiziol Zh Im I M Sechenova. 1998 Nov; 84(11):1293-302.
Review Cell phone use and acoustic neuroma: the need for standardized questionnaires and access to industry data. [Surg Neurol. 2009]
Review Cell phone use and acoustic neuroma: the need for standardized questionnaires and access to industry data.
Han YY, Kano H, Davis DL, Niranjan A, Lunsford LD. Surg Neurol. 2009 Sep; 72(3):216-22; discussion 222. Epub 2009 Mar 27.

See reviews... See all...

Cited by 2 PubMed Central articles

Effect of radio-frequency electromagnetic radiations (RF-EMR) on passive avoidance behaviour and hippocampal morphology in Wistar rats. [Ups J Med Sci. 2010]
Effect of radio-frequency electromagnetic radiations (RF-EMR) on passive avoidance behaviour and hippocampal morphology in Wistar rats.
Narayanan SN, Kumar RS, Potu BK, Nayak S, Bhat PG, Mailankot M. Ups J Med Sci. 2010 May; 115(2):91-6.
Spatial memory performance of Wistar rats exposed to mobile phone. [Clinics (Sao Paulo). 2009]
Spatial memory performance of Wistar rats exposed to mobile phone.
Narayanan SN, Kumar RS, Potu BK, Nayak S, Mailankot M. Clinics (Sao Paulo). 2009; 64(3):231-4.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Upregulation of specific mRNA levels in rat brain after cell phone exposure.
Upregulation of specific mRNA levels in rat brain after cell phone exposure.
Electromagn Biol Med. 2008 ;27(2):147-54.

PubMed
Internalization of the ultra-thin ideal: positive implicit associations with und...
Internalization of the ultra-thin ideal: positive implicit associations with underweight fashion models are associated with drive for thinness in young women.
Eat Disord. 2008 Jul-Sep ;16(4):294-307.

PubMed
Sustained-release pellets prepared by combination of wax matrices and double-lay...
Sustained-release pellets prepared by combination of wax matrices and double-layer coatings for extremely water-soluble drugs.
Drug Dev Ind Pharm. 2008 Jun ;34(6):569-76.

PubMed
Comparison of in vitro eye irritation potential by bovine corneal opacity and pe...
Comparison of in vitro eye irritation potential by bovine corneal opacity and permeability (BCOP) assay to erythema scores in human eye sting test of surfactant-based formulations.
Cutan Ocul Toxicol. 2008 ;27(2):77-85.

PubMed
Cerebrospinal fluid catecholamine metabolites in HIV-infected patients.
Cerebrospinal fluid catecholamine metabolites in HIV-infected patients.
J Neurosci Res. 1991 Mar ;28(3):406-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: