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1: World J Surg Oncol. 2008 Jun 18;6:62.Click here to read Click here to read Links

Late widespread skeletal metastases from myxoid liposarcoma detected by MRI only.

Hanna SA, Qureshi YA, Bayliss L, David LA, O'Donnell P, Judson IR, Briggs TW.

London Bone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK. sammyhanna@hotmail.com

BACKGROUND: Myxoid liposarcoma is the second most commonly occurring sub-type of liposarcomas. In contrast to other soft tissue sarcomas, it is known to have a tendency to spread toward extrapulmonary sites, such as soft tissues, retroperitoneum, and the peritoneal surface. Bony spread, however, is not as common. CASE PRESENTATION: We report an unusual case of diffuse skeletal metastases from myxoid liposarcoma occurring 13 years after treatment of the primary tumour in the left lower limb. The skeletal spread of the disease was demonstrated on MRI only after other imaging modalities (plain radiography, CT and TC99 bone scans) had failed to detect these metastases. CONCLUSION: MRI is an extremely sensitive and specific screening tool in the detection of skeletal involvement in these types of sarcomas, and therefore, should be a part of the staging process.

PMID: 18564429 [PubMed - indexed for MEDLINE]

PMCID: PMC2440383