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JNMA J Nepal Med Assoc. 2008 Jan-Mar;47(169):34-7.

Reye syndrome: a case report with review of literature.

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  • 1Department of Pathology, Manipal College of Medical Sciences and Manipal Teaching Hospital, Pokhara, Nepal.


Here we describe a case of Reye syndrome diagnosed at postmortem liver biopsy of a three-year old girl who presented with vomiting, low grade fever for three days and loss of consciousness for 18 hours. Clinically, the differential diagnoses were meningitis, encephalitis and septicemia. No history of past illness or any drug ingestion including aspirin were present. Laboratory investigations indicated a diagnosis of Reye syndrome. The child was given supportive treatment but died after two days of admission and postmortem needle-biopsy of the liver showed microvesicular steatosis consistent with Reye syndrome.

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