Epidemiology. 2008 Jul;19(4):588-9.

Too little of a good thing: a paradox of moderate infection control.

Source

Division of Social Medicine and Health Inequalities Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. tcohen@hsph.harvard.edu

Abstract

Epidemic theory dictates that a reduction in the force of infection by a pathogen is associated with an increase in the average age at which individuals are exposed. For those pathogens that cause more severe disease among hosts of an older age, interventions that limit transmission can paradoxically increase the burden of disease in a population.

Comment on

Epidemiology. 2008 Jul;19(4):581-7.

PMID:: 18552592; [PubMed - indexed for MEDLINE]
PMCID:: PMC2652751

Free PMC Article

Publication Types, MeSH Terms, Grant Support

Publication Types

Comment

MeSH Terms

Grant Support

K08 AI055985-06/AI/NIAID NIH HHS/United States

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Infection Control - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Review Microbial agents associated with waterborne diseases. [Crit Rev Microbiol. 2002]
Review Microbial agents associated with waterborne diseases.
Leclerc H, Schwartzbrod L, Dei-Cas E. Crit Rev Microbiol. 2002; 28(4):371-409.
Use of host population reduction to control wildlife infection: rabbits and paratuberculosis. [Epidemiol Infect. 2009]
Use of host population reduction to control wildlife infection: rabbits and paratuberculosis.
Davidson RS, Marion G, White PC, Hutchings MR. Epidemiol Infect. 2009 Jan; 137(1):131-8. Epub 2008 Apr 18.
Working awareness of healthcare workers regarding sterilisation, disinfection, and transmission of bloodborne infections and device-related infections at a tertiary care referral centre in north India. [J Hosp Infect. 2010]
Working awareness of healthcare workers regarding sterilisation, disinfection, and transmission of bloodborne infections and device-related infections at a tertiary care referral centre in north India.
Taneja N, Gill SS, Biswal M, Kumar A, Gupta AK, Parwej S, Sharma M. J Hosp Infect. 2010 Jul; 75(3):244-5. Epub 2010 Mar 19.
Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa. [Lancet. 1997]
Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa.
Snow RW, Omumbo JA, Lowe B, Molyneux CS, Obiero JO, Palmer A, Weber MW, Pinder M, Nahlen B, Obonyo C, et al. Lancet. 1997 Jun 7; 349(9066):1650-4.
Review Acinetobacter infection. [N Engl J Med. 2008]
Review Acinetobacter infection.
Munoz-Price LS, Weinstein RA. N Engl J Med. 2008 Mar 20; 358(12):1271-81.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC

Recent activity

Clear Turn Off Turn On

Too little of a good thing: a paradox of moderate infection control.
Too little of a good thing: a paradox of moderate infection control.
Epidemiology. 2008 Jul ;19(4):588-9.

PubMed
Model selection and health effect estimation in environmental epidemiology.
Model selection and health effect estimation in environmental epidemiology.
Epidemiology. 2008 Jul ;19(4):558-60.

PubMed
Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase.
Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase.
Cell. 1991 Jul 26 ;66(2):347-60.

PubMed
Gametocyte clearance in uncomplicated and severe Plasmodium falciparum malaria a...
Gametocyte clearance in uncomplicated and severe Plasmodium falciparum malaria after artesunate-mefloquine treatment in Thailand.
Korean J Parasitol. 2008 Jun ;46(2):65-70.

PubMed
Effect of methadone treatment on incarceration rates among injection drug users.
Effect of methadone treatment on incarceration rates among injection drug users.
Eur Addict Res. 2008 ;14(3):143-9. Epub 2008 Jun 13 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: