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Br J Ophthalmol. 1991 Jul;75(7):407-10.

Cis-platinum chemotherapy for ocular basal cell carcinoma.

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  • 1Department of Ophthalmology, Manhattan Eye, Ear, and Throat Hospital, New York City.


We have used intravenous cis-platinum chemotherapy in the treatment of three patients with basal cell carcinoma of the lid extending into the orbit. Cis-platinum chemotherapy caused a reduction in tumour size and thereby delayed surgery in all cases. It allowed for local resection in one case, appeared to delay a patient's exenteration in a second case, and was used prior to radiotherapy in a third case. While not curative, cis-platinum may be useful as an adjuvant to decrease tumour mass prior to local excision and for patients who refuse or must delay exenteration.

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