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Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor.
Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM.
J Biol Chem. 2008 Aug 8;283(32):22166-76. Epub 2008 Jun 10.
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