Med Arh. 2008;62(1):45-8.

[Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy].

[Article in Bosnian]

Source

Institut za Farmakologiju, Klinicku farmakologiju i toksikologiju, Medicinski Fakultet u Sarajevu. fbecic@dic.unsa.ba

Abstract

Alpha lipoic acid is important intramolecular redox system. It is coenzyme of piruvate dehydrogenase and ketoglutarate dehydrogenase. Alpha lipoic acid has enzymatic and cytoprotective effect. It has key role in citric acid cycle, as a coenzyme. Therapeutic efficacy of alpha lipoic acid in diabetic neuropathy is based on reaction with free radicals and lipophylic antioxydans properties. Clinical studies results showed efficacy and safety of alpha liponic acid application in patients with diabetic neuropathy.

PMID:: 18543755; [PubMed - indexed for MEDLINE]

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