A new oxygenated ursane derivative from Canthium multiflorum

Maminata Traoré; Jerzy W Jaroszewski; Carl Erik Olsen; Jean Bosco Ouédraogo; Guissou I Pierre; Odile G Nacoulma; T Robert Guiguemdé; S Brøgger Christensen

doi:10.1055/s-2008-1034372

A new oxygenated ursane derivative from Canthium multiflorum

Planta Med. 2008 Apr;74(5):560-2. doi: 10.1055/s-2008-1034372.

Authors

Maminata Traoré¹, Jerzy W Jaroszewski, Carl Erik Olsen, Jean Bosco Ouédraogo, Guissou I Pierre, Odile G Nacoulma, T Robert Guiguemdé, S Brøgger Christensen

Affiliation

¹ Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark.

PMID: 18543152
DOI: 10.1055/s-2008-1034372

Abstract

A new ursane derivative, 3-oxo-15alpha,19alpha-dihydroxyursa-1,12-dien-28-oic acid, was isolated from the roots of Canthium multiflorum (Rubiaceae) along with 10-O-acetylgeniposidic acid, 6,7-dimethoxycoumarin, hymexelsin, scopoletin, and 5,6,7-trimethoxycoumarin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Microbial Sensitivity Tests
Plant Extracts / pharmacology*
Plant Roots / chemistry
Plasmodium falciparum / drug effects*
Rubiaceae / chemistry*
Triterpenes / chemistry
Triterpenes / isolation & purification*
Triterpenes / pharmacology

Substances

3-oxo-15alpha,19alpha-dihydroxyursa-1,12-dien-28-oic acid
Plant Extracts
Triterpenes