Send to

Choose Destination
See comment in PubMed Commons below
Opt Express. 2008 Mar 3;16(5):3197-203.

Impact of velocity distribution assumption on simplified laser speckle imaging equation.

Author information

  • 1Optics Department, Instituto Nacional de Astrofísica, Optica y Electrónica, Luis Enrique Erro No. 1, Puebla, 72840, México.


Since blood flow is tightly coupled to the health status of biological tissue, several instruments have been developed to monitor blood flow and perfusion dynamics. One such instrument is laser speckle imaging. The goal of this study was to evaluate the use of two velocity distribution assumptions (Lorentzian- and Gaussian-based) to calculate speckle flow index (SFI) values. When the normalized autocorrelation function for the Lorentzian and Gaussian velocity distributions satisfy the same definition of correlation time, then the same velocity range is predicted for low speckle contrast (0 < C < 0.6) and predict different flow velocity range for high contrast. Our derived equations form the basis for simplified calculations of SFI values.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Optical Society of America Icon for PubMed Central
    Loading ...
    Write to the Help Desk