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Res Microbiol. 2008 Jun;159(5):367-73. doi: 10.1016/j.resmic.2008.04.006. Epub 2008 May 1.

Viral diversity and dynamics in an infant gut.

Author information

  • 1College of Marine Sciences, University of South Florida, 140 Seventh Avenue South, Saint Petersburg, FL 33701, USA. mya@marine.usf.edu

Abstract

Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula, suggesting a non-dietary initial source of viruses. Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between 1 and 2 weeks of age.

PMID:
18541415
[PubMed - indexed for MEDLINE]
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