Department of Clinical Research, Development, and Medical Affairs, Vaccines for Viral Diseases, GlaxoSmithKline, King of Prussia, PA 19406, USA.
The immunogenicity and safety of hepatitis A vaccine and pneumococcal conjugate vaccine, administered separately or concomitantly in children 15 months of age, were evaluated. After completed vaccinations, antihepatitis A and antipneumococcal geometric mean concentrations were similar across groups. Both vaccines were well-tolerated when given concomitantly during the second year of life.