Send to:

Choose Destination
See comment in PubMed Commons below
Neurodegener Dis. 2008;5(5):296-303. doi: 10.1159/000135614. Epub 2008 Jun 3.

Towards noninvasive molecular fluorescence imaging of the human brain.

Author information

  • 1Clinic of Neurology, Charité - Universitatsmedizin Berlin, Berlin, Germany.


Fluorescence molecular brain imaging is a new modality allowing the detection of specific contrast agents down to very low concentration ranges (picomolar) in disease models. Here we demonstrate a first noninvasive application of fluorescence imaging in the human brain, where concentrations down to about 100 nM of a nonspecific dye were detected. We argue that due to its high sensitivity, optical molecular imaging of the brain is feasible, which - together with its bedside applicability - makes it a promising technique for use in patients.

(c) 2008 S. Karger AG, Basel

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for S. Karger AG, Basel, Switzerland
    Loading ...
    Write to the Help Desk