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    Acta Ophthalmol. 2009 May;87(3):349-52. Epub 2008 Jun 28.

    Therapeutic efficacy of intravitreal bevacizumab on posterior uveitis complicated by neovascularization.

    Kurup S, Lew J, Byrnes G, Yeh S, Nussenblatt R, Levy-Clarke G.

    Department of Ophthalmology, Wake Forest University Eye Centre, Winston Salem, North Carolina 27101, USA. skurup@wfubmc.edu

    PURPOSE: To evaluate the therapeutic effect of intravitreal bevacizumab in patients with uveitis-associated choroidal/retinal neovascularization. METHODS: Two female patients (40 years, 15 years) with posterior uveitis, (one presumed ocular sarcoidosis, one lupus) were evaluated for neovascularization of the posterior segment. Both patients were given a single dose of 1.25 mg intravitreal bevacizumab. RESULTS: Significant anatomical and functional recovery was evident in both patients within a few weeks. CONCLUSION: In selected uveitic patients, bevacizumab may be an option for managing neovascularization.

    PMID: 18513266 [PubMed - indexed for MEDLINE]

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