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1: Eur J Pediatr. 2009 Feb;168(2):233-5. Epub 2008 May 22.Click here to read Links

Asplenia and functional hyposplenism in autoimmune polyglandular syndrome type 1.

Pollak U, Bar-Sever Z, Hoffer V, Marcus N, Scheuerman O, Garty BZ.

Department of Pediatrics B, Schneider Children's Medical Center of Israel, Petah Tiqwa 49202, Israel.

Asplenia was diagnosed in four patients with autoimmune polyendocrine syndrome type-I (APS-I): two children, aged 2-4 years, from the same family and two adults, the father of the two children and his cousin. We have observed a worsening in splenic function in the children during a follow-up of a few years. Patients with APS-I should be evaluated for splenic function, since splenic dysfunction has important therapeutic implications, especially in children.

PMID: 18496713 [PubMed - indexed for MEDLINE]

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