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    J Am Chem Soc. 2008 Jun 18;130(24):7558-9. Epub 2008 May 21.

    Ring-opening reactions of aromatic N-heterocycles by scandium and yttrium alkyl complexes.

    Source

    Department of Chemistry & Biochemistry, University of California, Los Angeles, California 90095, USA.

    Abstract

    The C-N bond in aromatic N-heterocycles is a strong bond, its cleaving involving mostly examples of metal-element multiple bonds. We report on the C-C coupling of two molecules of an aromatic N-heterocycle mediated by scandium and yttrium benzyl complexes supported by a ferrocene 1,1'-diamide ligand. The reaction with 1-methylimidazole leads, ultimately, to the formation of a ring-opened imidazole coupled to a 1-methylimidazole fragment, a structure showing extended conjugation of double bonds. The experimental evidence agrees with involvement of only sigma bonds in these transformations.

    PMID:
    18491906
    [PubMed]

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