Glycemic control and reduction of deep sternal wound infection rates: a multidisciplinary approach

Arch Surg. 2008 May;143(5):451-6. doi: 10.1001/archsurg.143.5.451.

Abstract

Objective: To demonstrate the multidisciplinary interactions and tools required to effect changes in the processes of care to achieve tight glycemic control (TGC) and reduce deep sternal wound infection (DSWI) rates in patients undergoing cardiac surgery.

Design: A retrospective cohort analysis comparing the rate of DSWI before and after implementing a multidisciplinary TGC initiative.

Setting: A cardiac surgical program in a tertiary care community hospital in New England.

Patients: A total of 3065 consecutive adult patients undergoing cardiac surgery who were operated on between January 1, 2004, and December 31, 2006.

Interventions: Evidence demonstrating the relationship between hyperglycemia and DSWI was presented to the multidisciplinary group caring for patients undergoing cardiac surgery. In addition, special emphasis was placed on nursing feedback and in-service training. A cumbersome glycemic management text protocol was replaced with a novel color-coded bedside tool (nomogram) to guide the bedside management of hyperglycemia. Subsequently, an algorithm for the transition to a home regimen was developed, which further improved standardization of care and ease of management.

Main outcome measures: Hourly blood glucose level monitoring and the incidence of DSWI.

Results: Eighteen months after the new program was initiated, the DSWI rate decreased by more than 60% from 2.6% to 1.0%, when compared with the preceding 18 months (P < .001).

Conclusion: A TGC program using a novel tool in a multidisciplinary setting was successfully and safely established, resulting in sustained improvement in the DSWI rate.

MeSH terms

  • Adult
  • Algorithms
  • Blood Glucose / metabolism
  • Cardiac Surgical Procedures / adverse effects*
  • Cohort Studies
  • Humans
  • Hyperglycemia / diagnosis
  • Hyperglycemia / etiology
  • Hyperglycemia / prevention & control*
  • Hypoglycemia / diagnosis
  • Hypoglycemia / etiology
  • Hypoglycemia / prevention & control*
  • Hypoglycemic Agents / administration & dosage*
  • Infusions, Parenteral
  • Insulin / administration & dosage*
  • Nomograms
  • Retrospective Studies
  • Sternum
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / metabolism
  • Surgical Wound Infection / prevention & control*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin