Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Abnorm Psychol. 2008 May;117(2):268-77. doi: 10.1037/0021-843X.117.2.268.

Life events as predictors of mania and depression in bipolar I disorder.

Author information

  • 1Department of Psychology, University of Miami, Coral Gables, FL 33124-0721, USA. sjohnson@miami.edu

Erratum in

  • J Abnorm Psychol. 2008 Aug;117(3):698. Cueller, Amy K [corrected to Cuellar, Amy K].

Abstract

To date, few prospective studies of life events and bipolar disorder are available, and even fewer have separately examined the role of life events in depression and mania. The goal of this study was to prospectively examine the role of negative and goal-attainment life events as predictors of the course of bipolar disorder. One hundred twenty-five individuals with bipolar I disorder were interviewed monthly for an average of 27 months. Negative and goal-attainment life events were assessed with the Life Events and Difficulties Schedule. Changes in symptoms were evaluated using the Modified Hamilton Rating Scale for Depression and the Bech-Rafaelsen Mania Scale. The clearest results were obtained for goal-attainment life events, which predicted increases in manic symptoms over time. Negative life events predicted increases in depressive symptoms within regression models but were not predictive within multilevel modeling of changes in depressive symptoms. Given different patterns for goal attainment and negative life events, it appears important to consider specific forms of life events in models of bipolar disorder.

PMID:
18489203
[PubMed - indexed for MEDLINE]
PMCID:
PMC2862221
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Psychological Association Icon for PubMed Central
    Loading ...
    Write to the Help Desk