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J Adolesc Health. 2008 Jun;42(6):637-9. doi: 10.1016/j.jadohealth.2007.11.147. Epub 2008 Mar 6.

Adolescent-onset substance use disorders predict young adult mortality.

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  • 1Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.


This study determined whether adolescent-onset substance use disorders (SUDs) prospectively predicted early mortality. Among 870 adolescents, 21 young adulthood deaths were observed. Adolescent SUDs, as well as gender, ethnic group, hazardous substance use, and drug trafficking, predicted these deaths. Among African American males with SUDs, 23% died by age 25.

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