Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Jun;25(6):722-31.

Significance, chemistry and determination of ergot alkaloids: a review.

Source

Department for Agrobiotechnology (IFA Tulln), University of Natural Resources and Applied Life Sciences Vienna, Tulln, Austria. rudolf.krska@boku.ac.at

Abstract

The purpose of this paper is to summarize the most relevant and recent information available on ergot alkaloids. This includes information about their occurrence, toxicity, chemistry, statutory limits, and their significance in feed and food. Recently, in 2005, the European Food Safety Authority (EFSA) concluded that validated analytical methods for the quantification of ergot alkaloids in feed materials are needed. For that reason, the major focus of the present paper is to report on the latest developments for the determination of major ergot alkaloids and their epimers in cereals and cereal-derived products. Information about the stability and the availability of calibrants, sampling issues, extraction and clean-up strategies, and a variety of final separation and detection techniques is provided. The recently developed liquid chromatography-tandem mass spectrometric methods (LC-MS/MS) for the simultaneous quantification and identification of ergot alkaloids are given special consideration.

PMID:: 18484300; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Ergot Alkaloids

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Molecular Biology Databases

ERGOT ALKALOID - HSDB

Supplemental Content

Save items

Related citations in PubMed

Simultaneous determination of six major ergot alkaloids and their epimers in cereals and foodstuffs by LC-MS-MS. [Anal Bioanal Chem. 2008]
Simultaneous determination of six major ergot alkaloids and their epimers in cereals and foodstuffs by LC-MS-MS.
Krska R, Stubbings G, Macarthur R, Crews C. Anal Bioanal Chem. 2008 May; 391(2):563-76. Epub 2008 Apr 16.
Determination of ergot alkaloids: purity and stability assessment of standards and optimization of extraction conditions for cereal samples. [J AOAC Int. 2008]
Determination of ergot alkaloids: purity and stability assessment of standards and optimization of extraction conditions for cereal samples.
Krska R, Berthiller F, Schuhmacher R, Nielsen KF, Crews C. J AOAC Int. 2008 Nov-Dec; 91(6):1363-71.
Liquid chromatographic method for the determination of ergot alkaloids in cereal grains. [Methods Mol Biol. 2001]
Liquid chromatographic method for the determination of ergot alkaloids in cereal grains.
Lombaert GA. Methods Mol Biol. 2001; 157:215-24.
Review Chromatographic methods for the simultaneous determination of mycotoxins and their conjugates in cereals. [Int J Food Microbiol. 2007]
Review Chromatographic methods for the simultaneous determination of mycotoxins and their conjugates in cereals.
Berthiller F, Sulyok M, Krska R, Schuhmacher R. Int J Food Microbiol. 2007 Oct 20; 119(1-2):33-7. Epub 2007 Jul 31.
Review Mycotoxin analysis: an update. [Food Addit Contam Part A Chem ...]
Review Mycotoxin analysis: an update.
Krska R, Schubert-Ullrich P, Molinelli A, Sulyok M, MacDonald S, Crews C. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Feb; 25(2):152-63.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Significance, chemistry and determination of ergot alkaloids: a review.
Significance, chemistry and determination of ergot alkaloids: a review.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Jun ;25(6):722-31.

PubMed
Speech and language development in cri du chat syndrome: a critical review.
Speech and language development in cri du chat syndrome: a critical review.
Clin Linguist Phon. 2008 Jun ;22(6):443-57.

PubMed
Assessment of leech therapy for knee osteoarthritis: a randomized study.
Assessment of leech therapy for knee osteoarthritis: a randomized study.
Acta Orthop. 2008 Apr ;79(2):235-43.

PubMed
Preoperative chemotherapy is safe in early breast cancer, even after 10 years of...
Preoperative chemotherapy is safe in early breast cancer, even after 10 years of follow-up; clinical and translational results from the EORTC trial 10902.
Breast Cancer Res Treat. 2009 May ;115(1):101-13. Epub 2008 May 18 .

PubMed
The association between major birth defects and preterm birth.
The association between major birth defects and preterm birth.
Matern Child Health J. 2009 Mar ;13(2):164-75. Epub 2008 May 17 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: