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Chem Biol. 2008 May;15(5):421-3. doi: 10.1016/j.chembiol.2008.04.007.

Computational design of enzymes.

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  • 1Institute of Biophysics and Physical Biochemistry, University of Regensburg, Regensburg, Germany.

Abstract

The de novo design of enzymes with activities not found in natural biocatalysts is a major challenge for molecular biology. Sophisticated computational methods have recently led to impressive progress in this exciting and rapidly evolving field (Röthlisberger et al., 2008; Jiang et al., 2008).

PMID:
18482694
[PubMed - indexed for MEDLINE]
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