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Obes Surg. 2008 Sep;18(9):1109-11. doi: 10.1007/s11695-008-9544-5. Epub 2008 May 14.

Pregnancy in formerly type 2 diabetes obese women following biliopancreatic diversion for obesity.

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  • 1Dipartimento di Discipline Chirurgiche, Facolt√† di Medicina e Chirurgia, Universit√† di Genova, Genoa, Italy. adami@unige.it

Abstract

BACKGROUND:

This study describes the pregnancy of previously obese women with type 2 diabetic who reduced body weight and normalized serum glucose level following biliopancreatic diversion (BPD) for obesity.

METHODS:

A subset of ten women who had type 2 diabetes prior to BPD and who developed pregnancy after the operation was retrospectively identified.

RESULTS:

All pregnancies were completely normal, and serum glucose levels remained within the physiological range throughout all the pregnancy. These post-diabetic women delivered 13 infants in good health with a normal birth weight and no case of macrosomia.

CONCLUSIONS:

These data are a clinical confirmation of the post-BPD improvement of beta-cell response to increased functional demand in obese patients with preoperative type 2 diabetes.

PMID:
18478305
[PubMed - indexed for MEDLINE]
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