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J Math Biol. 2009 Jan;58(1-2):57-80. doi: 10.1007/s00285-008-0180-4. Epub 2008 May 14.

Multiple objects tracking in fluorescence microscopy.

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  • 1Max-Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307, Dresden, Germany.


Many processes in cell biology are connected to the movement of compact entities: intracellular vesicles and even single molecules. The tracking of individual objects is important for understanding cellular dynamics. Here we describe the tracking algorithms which have been developed in the non-biological fields and successfully applied to object detection and tracking in biological applications. The characteristics features of the different algorithms are compared.

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