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Epidemiology. 2008 Jul;19(4):563-70. doi: 10.1097/EDE.0b013e31816d652d.

Temperature and mortality in nine US cities.

Author information

  • 1Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA. azanobet@hsph.harvard.edu

Abstract

BACKGROUND:

Extreme temperatures have been associated with increased mortality worldwide. The extent to which air pollutants may confound or modify this association remains unclear.

METHODS:

We examined the association between mean apparent temperature and total mortality in 9 cities across the United States during the warm season (May to September) from 1999 to 2002. We applied case-crossover and time-series analyses, adjusting for day of the week and season in time-series analysis. City-specific estimates were then combined using a meta-analysis. A total of 213,438 deaths for all causes occurred in these cities during the study period.

RESULTS:

We found that mortality increased with apparent temperature. A 5.5 degrees C (10 degrees F) increase in apparent temperature was associated with an increase in mortality of 1.8% (95% confidence interval = 1.09% to 2.5%) when using case-crossover analysis and with an increase of 2.7% (2.0% to 3.5%) using the time-series analysis.

CONCLUSIONS:

This study provides evidence of increased mortality due to elevated apparent temperature exposure, with no confounding or effect modification due to air pollution.

PMID:
18467963
[PubMed - indexed for MEDLINE]
PMCID:
PMC3722554
Free PMC Article

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