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1: Blood. 2008 May 15;111(10):4834-5.Click here to read Links
Erratum in:
Blood. 2008 Aug 15;112(4):1546.
Comment on:
Blood. 2008 May 15;111(10):4944-53.

The three musketeers of HSC development.

Ekker S.

Mayo Clinic, USA.

Hematopoietic stem cells (HSCs) are a key paradigm system for stem cell therapy applications. How these cells change from their multipotent to lineage-restricted cell states is still not fully understood. In this issue of Blood, McKinney-Freeman and colleagues show that members of a single transcription factor gene family are used in diverse and dynamic ways to implement this critical organogenesis program.

PMID: 18467601 [PubMed]