Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Biomed Opt. 2008 Mar-Apr;13(2):020507. doi: 10.1117/1.2907791.

Sentinel lymph node detection ex vivo using ultrasound-modulated optical tomography.

Author information

  • 1Washington University in Saint Louis, Optical Imaging Laboratory, Department of Biomedical Engineering, Campus Box 1097, One Brookings Drive, Saint Louis, Missouri 63130-4899, USA.

Abstract

We apply ultrasound-modulated optical tomography (UOT) to image ex-vivo methylene-blue-dyed sentinel lymph nodes embedded in 3.2-cm-thick chicken breast tissues. The UOT system is implemented for the first time using ring-shaped light illumination, intense acoustic bursts, and charge-coupled device (CCD) camera-based speckle contrast detection. Since the system is noninvasive, nonionizing, portable, relatively cost effective, and easy to combine with photoacoustic imaging and single element ultrasonic pulse-echo imaging, UOT can potentially be a good imaging modality for the detection of sentinel lymph nodes in breast cancer staging in vivo.

PMID:
18465949
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Write to the Help Desk