J Pediatr Hematol Oncol. 2008 May;30(5):369-72.

Intracerebral presentation of Hodgkin disease mimicking meningioma in a young woman: case presentation with literature review.

Apollonsky N, Edelman M, Johnson A, Bhuiya T, Karayalcin G.

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Division of Pediatric Hematology/Oncology and Stem Cell Transplantation, Department of Pediatrics, Schneider Children's Hospital, New Hyde Park, NY, USA.

Abstract

Intracranial involvement of the Hodgkin disease (HD) is a rare entity. Until now, 9 cases of initial presentation of the HD as a brain tumor with appropriate morphologic and histochemical confirmation were reported. Of the 9 patients, 6 had isolated primary intracranial HD and 3 patients after further investigation were found to have extracranial involvement. Seven patients had nodular sclerosing histology, 1 had mixed cellularity, and in 1 case histology was not reported. We describe a patient with systemic nodular sclerosing HD, who initially presented with a brain mass mimicking meningioma and was found to have disseminated lymphadenopathy and bone involvement.

PMID:: 18458571; [PubMed - indexed for MEDLINE]

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