Ann Intern Med. 2008 May 6;148(9):662-70.

Narrative review: buprenorphine for opioid-dependent patients in office practice.

Source

Yale University School of Medicine, New Haven, Connecticut 06520-8093, USA. lynn.sullivan@yale.edu

Abstract

The profile of opioid dependence in the United States is changing. Abuse of prescription opioids is more common than that of illicit opioids: Recent data indicate that approximately 1.6 million persons abuse or are dependent on prescription opioids, whereas 323,000 abuse or are dependent on heroin. Despite this prevalence, nearly 80% of opioid-dependent persons remain untreated. One option for expanding treatment is the use of buprenorphine and the buprenorphine-naloxone combination. Buprenorphine is a partial opioid agonist that can be prescribed by trained physicians and dispensed at pharmacies. This article addresses the clinical presentation of a patient with opioid dependence and describes the relatively new practice of office-based treatment with buprenorphine-naloxone. The different components of treatment; the role of the physician who provides this treatment; and the logistics of treating this growing, multifaceted patient population are also examined.

PMID:: 18458279; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Review Opioid dependence treatment, including buprenorphine/naloxone. [Ann Pharmacother. 2002]
Review Opioid dependence treatment, including buprenorphine/naloxone.
Raisch DW, Fye CL, Boardman KD, Sather MR. Ann Pharmacother. 2002 Feb; 36(2):312-21.
Treating opioid addiction with buprenorphine-naloxone in community-based primary care settings. [Ann Fam Med. 2007]
Treating opioid addiction with buprenorphine-naloxone in community-based primary care settings.
Mintzer IL, Eisenberg M, Terra M, MacVane C, Himmelstein DU, Woolhandler S. Ann Fam Med. 2007 Mar-Apr; 5(2):146-50.
Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers. [Psychopharmacology (Berl). 2000]
Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers.
Strain EC, Stoller K, Walsh SL, Bigelow GE. Psychopharmacology (Berl). 2000 Mar; 148(4):374-83.
Opioid drug utilization and cost outcomes associated with the use of buprenorphine-naloxone in patients with a history of prescription opioid use. [J Manag Care Pharm. 2008]
Opioid drug utilization and cost outcomes associated with the use of buprenorphine-naloxone in patients with a history of prescription opioid use.
Kaur AD, McQueen A, Jan S. J Manag Care Pharm. 2008 Mar; 14(2):186-94.
Review Opioid dependence: rationale for and efficacy of existing and new treatments. [Clin Infect Dis. 2006]
Review Opioid dependence: rationale for and efficacy of existing and new treatments.
Fiellin DA, Friedland GH, Gourevitch MN. Clin Infect Dis. 2006 Dec 15; 43 Suppl 4:S173-7.

See reviews... See all...

Cited by 3 PubMed Central articles

Clinic-based treatment of opioid-dependent HIV-infected patients versus referral to an opioid treatment program: A randomized trial. [Ann Intern Med. 2010]
Clinic-based treatment of opioid-dependent HIV-infected patients versus referral to an opioid treatment program: A randomized trial.
Lucas GM, Chaudhry A, Hsu J, Woodson T, Lau B, Olsen Y, Keruly JC, Fiellin DA, Finkelstein R, Barditch-Crovo P, et al. Ann Intern Med. 2010 Jun 1; 152(11):704-11.
Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone. [CMAJ. 2009]
Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone.
Dhalla IA, Mamdani MM, Sivilotti ML, Kopp A, Qureshi O, Juurlink DN. CMAJ. 2009 Dec 8; 181(12):891-6. Epub 2009 Dec 7.
Illicit drug use among women with children in the United States: 2002-2003. [Ann Epidemiol. 2009]
Illicit drug use among women with children in the United States: 2002-2003.
Simmons LA, Havens JR, Whiting JB, Holz JL, Bada H. Ann Epidemiol. 2009 Mar; 19(3):187-93.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Narrative review: buprenorphine for opioid-dependent patients in office practice...
Narrative review: buprenorphine for opioid-dependent patients in office practice.
Ann Intern Med. 2008 May 6 ;148(9):662-70.

PubMed
Systematic review: Hydroxyurea for the treatment of adults with sickle cell dise...
Systematic review: Hydroxyurea for the treatment of adults with sickle cell disease.
Ann Intern Med. 2008 Jun 17 ;148(12):939-55. Epub 2008 May 5 .

PubMed
Spinal dural arteriovenous fistula: a treatable cause of myelopathy.
Spinal dural arteriovenous fistula: a treatable cause of myelopathy.
CMAJ. 2008 May 6 ;178(10):1286-8.

PubMed
Activation of the unfolded protein response by deltaF508 CFTR.
Activation of the unfolded protein response by deltaF508 CFTR.
Am J Respir Cell Mol Biol. 2008 Oct ;39(4):448-57. Epub 2008 May 5 .

PubMed
Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evi...
Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.
Neurology. 2008 May 6 ;70(19):1699-706.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Narrative review: buprenorphine for opioid-dependent patients in office practice.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information