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Cell. 2008 May 2;133(3):395-7. doi: 10.1016/j.cell.2008.04.016.

Epigenome sequencing comes of age.

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  • 1Botany and Plant Sciences, University of California, Riverside, CA 92508, USA.


Epigenetic states are responsive to developmental and environmental signals, and as a consequence a eukaryotic cell can have many different epigenomes. In this issue of Cell, Lister et al. (2008) present the floral epigenome of Arabidopsis using next-generation sequencing technology to analyze both DNA methylation at single-base resolution and the expression of small RNAs.

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