Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
MRC Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, Department of Anatomy, University Walk, Bristol, BS8 1TD, UK.
Activity dependent modification of receptors in the post-synaptic density is a key determinant in regulating the strength of synaptic transmission during development and plasticity. A major mechanism for this recruitment and removal of postsynaptic proteins is the lateral diffusion in the plane of the plasma membrane. Therefore, the processes that regulate this lateral mobility are of fundamental importance. In recent years significant progress has been achieved using optical approaches such as single particle tracking (SPT) and fluorescence recovery after photobleach (FRAP). Here, we provide an overview of the principles and methodology of these techniques and highlight the contributions they have made to current understanding of protein mobility in the plasma membrane.
Images from this publication.See all images (2) Free text
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on