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    Nutr Rev. 2008 May;66(5):291-7.

    Vitamin D and blood pressure connection: update on epidemiologic, clinical, and mechanistic evidence.

    Martini LA, Wood RJ.

    Nutrition Department, School of Public Health, Sao Paulo University, Sao Paulo, Brazil.

    Hypertension is an important risk factor for cardiovascular and kidney disease. High blood pressure is a growing public health problem that is expected to affect 1.6 billion people worldwide by the year 2025. In light of emerging evidence of a widespread global problem of vitamin D deficiency, there has been increasing interest concerning the role of vitamin D in chronic disease. The recent publication of several studies, highlighted in this brief review, supports an association between vitamin D status and blood pressure. It remains to be determined what level of vitamin D status needs to be achieved in different subpopulations to assure the maximum benefit of vitamin D status on blood pressure.

    PMID: 18454816 [PubMed - indexed for MEDLINE]

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