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Nutr Rev. 2008 May;66(5):291-7. doi: 10.1111/j.1753-4887.2008.00035.x.

Vitamin D and blood pressure connection: update on epidemiologic, clinical, and mechanistic evidence.

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  • 1Nutrition Department, School of Public Health, Sao Paulo University, Sao Paulo, Brazil.


Hypertension is an important risk factor for cardiovascular and kidney disease. High blood pressure is a growing public health problem that is expected to affect 1.6 billion people worldwide by the year 2025. In light of emerging evidence of a widespread global problem of vitamin D deficiency, there has been increasing interest concerning the role of vitamin D in chronic disease. The recent publication of several studies, highlighted in this brief review, supports an association between vitamin D status and blood pressure. It remains to be determined what level of vitamin D status needs to be achieved in different subpopulations to assure the maximum benefit of vitamin D status on blood pressure.

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