AIDS. 2008 May 11;22(8):989-90.

Is there a role for etravirine in patients with Nonnucleoside reverse transcriptase inhibitor resistance?

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St. Stephens Centre, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.

Erratum in

AIDS. 2008 Sep 12;22(14):i.

Abstract

Etravirine is a next generation nonnucleoside reverse transcriptase inhibitor with activity against nonnucleoside reverse transcriptase inhibitor resistant HIV-1 virus. Susceptibility and virological response to etravirine is dependent on the type and number of nonnucleoside reverse transcriptase inhibitor resistance-associated mutations. We examined the predicted susceptibility of etravirine in patients experiencing virological failure secondary to nonnucleoside reverse transcriptase inhibitor resistance in our patient cohort.

PMID:: 18453859; [PubMed - indexed for MEDLINE]

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