Yonsei Med J. 2008 Apr 30;49(2):325-8.

Acute human immunodeficiency virus syndrome presenting with hemophagocytic lymphohistiocytosis.

Park KH, Yu HS, Jung SI, Shin DH, Shin JH.

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Department of Internal Medicine, Chonnam National University Hospital, 8 Hak-dong, Dong-gu, Gwangju 501-757, Korea.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) has been described in patients with advanced stages of human immunodeficiency virus (HIV) infection, but rarely occurs during the seroconversion stage of acute HIV infection. We report a case of acute HIV syndrome that presented with virus-associated HLH. The patient recovered spontaneously without any immunomodulating therapy. This case suggests that acute HIV infection should be included in the differential diagnosis of HLH and indicates that HLH associated with acute HIV infection can have a favorable outcome.

PMID:: 18452272; [PubMed - indexed for MEDLINE]
PMCID:: PMC2615318

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