Pediatrics. 2008 May;121(5):1062-8. doi: 10.1542/peds.2008-0564.

Use of soy protein-based formulas in infant feeding.

Bhatia J, Greer F; American Academy of Pediatrics Committee on Nutrition.

Collaborators (15)

Greer FR, Bhatia JJ, Daniels SR, Schneider MB, Silverstein J, Stettler N, Thomas DW, Baker RD Jr, Heyman MB, Blum-Kemelor D, Grummer-Strawn L, Hubbard VS, Marchand V, Silverman BM, Burrowes D.

Abstract

Soy protein-based formulas have been available for almost 100 years. Since the first use of soy formula as a milk substitute for an infant unable to tolerate a cow milk protein-based formula, the formulation has changed to the current soy protein isolate. Despite very limited indications for its use, soy protein-based formulas in the United States may account for nearly 25% of the formula market. This report reviews the limited indications and contraindications of soy formulas. It will also review the potential harmful effects of soy protein-based formulas and the phytoestrogens contained in these formulas.

Comment in

Caution with committee recommendations for soy protein-based formulas. [Pediatrics. 2008]
Caution with committee recommendations for soy protein-based formulas.Fine BR, Sehgal S. Pediatrics. 2008 Nov; 122(5):1156; author reply 1156.

PMID:: 18450914; [PubMed - indexed for MEDLINE]

Free full text

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Infant and Newborn Nutrition - MedlinePlus Health Information

Molecular Biology Databases

ALUMINUM - HSDB

Supplemental Content

Save items

Related citations in PubMed

Review Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life. [Am J Clin Nutr. 1998]
Review Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life.
Setchell KD, Zimmer-Nechemias L, Cai J, Heubi JE. Am J Clin Nutr. 1998 Dec; 68(6 Suppl):1453S-1461S.
Soy protein infant formulae and follow-on formulae: a commentary by the ESPGHAN Committee on Nutrition. [J Pediatr Gastroenterol Nutr. ...]
Soy protein infant formulae and follow-on formulae: a commentary by the ESPGHAN Committee on Nutrition.
ESPGHAN Committee on Nutrition, Agostoni C, Axelsson I, Goulet O, Koletzko B, Michaelsen KF, Puntis J, Rieu D, Rigo J, Shamir R, et al. J Pediatr Gastroenterol Nutr. 2006 Apr; 42(4):352-61.
Review Safety of soy-based infant formulas containing isoflavones: the clinical evidence. [J Nutr. 2004]
Review Safety of soy-based infant formulas containing isoflavones: the clinical evidence.
Merritt RJ, Jenks BH. J Nutr. 2004 May; 134(5):1220S-1224S.
American Academy of Pediatrics. Committee on Nutrition. Soy protein-based formulas: recommendations for use in infant feeding. [Pediatrics. 1998]
American Academy of Pediatrics. Committee on Nutrition. Soy protein-based formulas: recommendations for use in infant feeding.
American Academy of Pediatrics. Committee on Nutrition. Pediatrics. 1998 Jan; 101(1 Pt 1):148-53.
Review Soy protein for the prevention and treatment of children with cow-milk allergy. [Am J Clin Nutr. 1998]
Review Soy protein for the prevention and treatment of children with cow-milk allergy.
Businco L, Bruno G, Giampietro PG. Am J Clin Nutr. 1998 Dec; 68(6 Suppl):1447S-1452S.

See reviews... See all...

Cited by 16 PubMed Central articles

Extensively hydrolysed casein formula supplemented with Lactobacillus rhamnosus GG maintains hypoallergenic status: randomised double-blind, placebo-controlled crossover trial. [BMJ Open. 2012]
Extensively hydrolysed casein formula supplemented with Lactobacillus rhamnosus GG maintains hypoallergenic status: randomised double-blind, placebo-controlled crossover trial.
Muraro A, Hoekstra MO, Meijer Y, Lifschitz C, Wampler JL, Harris C, Scalabrin DM. BMJ Open. 2012; 2(2):e000637. Epub 2012 Mar 5.
Early-life soy exposure and age at menarche. [Paediatr Perinat Epidemiol. 2012]
Early-life soy exposure and age at menarche.
Adgent MA, Daniels JL, Rogan WJ, Adair L, Edwards LJ, Westreich D, Maisonet M, Marcus M. Paediatr Perinat Epidemiol. 2012 Mar; 26(2):163-75. Epub 2011 Dec 16.
Review Determinants of food allergy. [Immunol Allergy Clin North Am....]
Review Determinants of food allergy.
Masilamani M, Commins S, Shreffler W. Immunol Allergy Clin North Am. 2012 Feb; 32(1):11-33.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Use of soy protein-based formulas in infant feeding.
Use of soy protein-based formulas in infant feeding.
Pediatrics. 2008 May ;121(5):1062-8. doi: 10.1542/peds.2008-0564.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: