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    Methods Mol Biol. 2008;460:1-22.

    Toxicogenomics and classic toxicology: how to improve prediction and mechanistic understanding of human toxicity.

    Mendrick DL.

    Department of Toxicogenomics, Gene Logic Inc., Gaithersburg, Maryland, USA.

    The field of toxicogenomics has been advancing during the past decade or so since its origin. Most pharmaceutical companies are using it in one or more ways to improve their productivity and supplement their classic toxicology studies. Acceptance of toxicogenomics will continue to grow as regulatory concerns are addressed, proof of concept studies are disseminated more fully, and internal case studies show value for the use of this new technology in concert with classic testing.

    PMID: 18449480 [PubMed - indexed for MEDLINE]

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