Your browser version may not work well with NCBI's Web applications. More information here...
1: J Investig Allergol Clin Immunol. 2008;18(2):131-5.Links

Hypereosinophilia, hyper-IgE syndrome, and atopic dermatitis in a toddler with food hypersensitivity.

Estrada-Reyes E, Hernnández-Román MP, Gamboa-Marrufo JD, Valencia-Herrera A, Nava-Ocampo AA.

Hospital Angeles Metropolitano, México DF, Mexico. elizabeth.estradareyes@gmail.com

We describe a 20-month-old girl with hypereosinophilia, hyper-immunoglobulin (Ig) E syndrome, and atopic dermatitis. Her peripheral eosinophil count and IgE plasma levels were 2.65 x 10(9)/L and 6702 IU/mL, respectively. Specific IgE levels for a variety of foods and inhalants were high and single-blind food challenges were positive for cow's milk, hen's egg, oat, wheat, and soy. When the patient received an extensively hydrolyzed milk formula, an exclusion diet, and 2 mg/kg of prednisone daily, the atopic dermatitis partially improved. Further improvement was observed with 1 mg/kg of azathioprine daily. Long-term clinical response was satisfactory.We suggest that food hypersensitivity should be ruled out in patients with hypereosinophilia, hyper-IgE syndrome, and atopic dermatitis. Azathioprine may be a good therapeutic alternative for treatment in such cases.

PMID: 18447144 [PubMed - indexed for MEDLINE]

Click here to read

Patient Drug Information

  • Prednisone (Prednisone Intensol® , Sterapred® , Sterapred® DS)

    Prednisone is used alone or with other medications to treat the symptoms of low corticosteroid levels (lack of certain substances that are usually produced by the body and are needed for normal body functioning). Prednis...

  • Mercaptopurine (Purinethol® )

    Your doctor has ordered the drug mercaptopurine to help treat your illness. The drug is taken by mouth in tablet form.

  • Azathioprine (Azasan® , Imuran® )

    Azathioprine is used with other medications to prevent rejection of kidney transplants. It is also used to treat severe rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain and swellin...

  • Source: AHFS Consumer Medication Information