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    Parassitologia. 1991 Dec;33(2-3):219-23.

    Plasmodium falciparum malaria transmission indices in a highland village of the Ikopa River Valley near Antananarivo, Madagascar.

    Source

    Etablissement d'Enseignement Supérieur des Sciences, Université d'Antananarivo, Madagascar.

    Abstract

    Data are reported from a malaria survey carried out in June 1991 in the small village of Ankadimbazinba, near Miantso, about 45 km North-West of Antananarivo (Madagascar). The objective was to evaluate the level of transmission of P. falciparum by entomological, parasitological and serological indices. All indices were found consistent with the description of a focus of hyperendemic transmission dependent on the presence of An. funestus at high density, corresponding to more than 50 females per house collected by hand catch. The positivity rate for the circumsporozoite protein (CS) of P. falciparum in blood-fed or gravid An. funestus was 2.0% (11/562) in the house resting sample. The parasite rate in the village population was 47.9% reaching 68.4% in the 0-14 age group and the gametocyte rate in the total sample was 25.0%. The seroprevalence of P. falciparum antisporozoite antibodies was 40.0% in children under 15 years old, 84.2% in the 15-29 age group and 90.9% in the over 29 age group.

    PMID:
    1844515
    [PubMed - indexed for MEDLINE]

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