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Antimicrob Agents Chemother. 2008 Jul;52(7):2647-52. doi: 10.1128/AAC.01398-07. Epub 2008 Apr 28.

In vitro activity of telavancin against resistant gram-positive bacteria.

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  • 1Theravance, Inc., South San Francisco, CA 94080, USA.

Abstract

The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC(90), 0.5 to 1 microg/ml), streptococci (all MICs, < or =0.12 microg/ml), and VanB-type enterococci (all MICs, < or =2 microg/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.

PMID:
18443122
[PubMed - indexed for MEDLINE]
PMCID:
PMC2443888
Free PMC Article
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