Species distribution and in vitro antifungal susceptibility patterns of 75 clinical isolates of Fusarium spp. from northern Italy

Antimicrob Agents Chemother. 2008 Jul;52(7):2683-5. doi: 10.1128/AAC.00272-08. Epub 2008 Apr 28.

Abstract

Fusarium isolates from 75 Italian patients were identified by molecular methods, and their susceptibilities to antifungals were tested in vitro. Fusarium verticillioides was the species most frequently isolated from deep-seated infections, and F. solani was the species most frequently isolated from superficial infections. F. solani isolates showed high azole MICs, while F. verticillioides isolates showed low posaconazole MICs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology*
  • Base Sequence
  • DNA Primers / genetics
  • DNA, Fungal / genetics
  • Drug Resistance, Fungal
  • Fusarium / classification*
  • Fusarium / drug effects*
  • Fusarium / genetics
  • Fusarium / isolation & purification
  • Humans
  • Italy
  • Microbial Sensitivity Tests
  • Mycoses / drug therapy
  • Mycoses / microbiology
  • Species Specificity

Substances

  • Antifungal Agents
  • DNA Primers
  • DNA, Fungal