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Bioinformatics. 2008 Jun 15;24(12):1471-2. doi: 10.1093/bioinformatics/btn206. Epub 2008 Apr 25.

gpDB: a database of GPCRs, G-proteins, effectors and their interactions.

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  • 1Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 157 01, Greece.


gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors (GPCRs) and effectors, as well as information concerning known interactions between these molecules. The sequences are classified according to a hierarchy of different classes, families and subfamilies based on literature search. The main innovation besides the classification of G-proteins, GPCRs and effectors is the relational model of the database, describing the known coupling specificity of GPCRs to their respective alpha subunits of G-proteins, and also the specific interaction between G-proteins and their effectors, a unique feature not available in any other database.


http://bioinformatics.biol.uoa.gr/gpDB CONTACT: shamodr@biol.uoa.gr


Supplementary data are available at Bioinformatics online.

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