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Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W5-9. doi: 10.1093/nar/gkn201. Epub 2008 Apr 24.

NCBI BLAST: a better web interface.

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  • 1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.


Basic Local Alignment Search Tool (BLAST) is a sequence similarity search program. The public interface of BLAST,, at the NCBI website has recently been reengineered to improve usability and performance. Key new features include simplified search forms, improved navigation, a list of recent BLAST results, saved search strategies and a documentation directory. Here, we describe the BLAST web application's new features, explain design decisions and outline plans for future improvement.

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