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Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W336-40. doi: 10.1093/nar/gkn214. Epub 2008 Apr 25.

GenoWatch: a disease gene mining browser for association study.

Author information

  • 1National Genotyping Center (NGC) and Institute of Biomedical Sciences (IBMS), Academia Sinica, Taipei, Taiwan 11529, R.O.C.

Abstract

A human gene association study often involves several genomic markers such as single nucleotide polymorphisms (SNPs) or short tandem repeat polymorphisms, and many statistically significant markers may be identified during the study. GenoWatch can efficiently extract up-to-date information about multiple markers and their associated genes in batch mode from many relevant biological databases in real-time. The comprehensive gene information retrieved includes gene ontology, function, pathway, disease, related articles in PubMed and so on. Subsequent SNP functional impact analysis and primer design of a target gene for re-sequencing can also be done in a few clicks. The presentation of results has been carefully designed to be as intuitive as possible to all users. The GenoWatch is available at the website http://genepipe.ngc.sinica.edu.tw/genowatch.

PMID:
18440974
[PubMed - indexed for MEDLINE]
PMCID:
PMC2447740
Free PMC Article

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