Distribution of Bayes Factors Associated with C-Reactive Protein in Stage 1 of PARC Genome-wide Association Study
A quantile-quantile plot comparing the distribution of log10(Bayes Factor) in the PARC study with the distribution under the null (generated by computation of the log10[Bayes Factor] for all SNPs for five random phenotype vectors, each obtained by randomly permutation of the original phenotypes across individuals). The red line indicates a straight line through the origin with unit slope. The color purple indicates the points that relate to the SNPs in Table 2.

Strength of Evidence for Association between HNF1A SNP and CRP Phenotype in PARC and CHS Combined
The vertical lines represent log10(Bayes Factors) (y axis) for each SNP in a ∼200 kilobase region encompassing the HNF1A gene on chromosome 12. SNPs are numbered according to chromosomal position on the x axis. The color of the vertical line indicates whether the SNP was directly observed in PARC (green), directly observed in CHS (red), directly observed in both PARC and CHS (pink), or indirectly observed by imputation from the HapMap (black). The gray shaded region demarcates the 5′ and 3′ boundaries of the HNF1A gene. Highlighted in yellow is the 5 kilobase region containing the five intron-1 SNPs showing the strongest evidence of association with CRP.