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Neuron. 2008 Apr 24;58(2):165-7. doi: 10.1016/j.neuron.2008.04.007.

Schizophrenia: genome, interrupted.

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  • 1Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.


Structural chromosomal variation is increasingly recognized as an important contributor to human diseases, particularly those of neurodevelopment, such as autism. A current paper makes a significant advance to schizophrenia genetics by establishing an association with rare copy number variants (CNV), which are over-represented in neurodevelopmental genes.

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