Treatment of traumatic optic neuropathy: our experience of endoscopic optic nerve decompression

J Laryngol Otol. 2008 Dec;122(12):1325-9. doi: 10.1017/S0022215108002296. Epub 2008 Apr 28.

Abstract

Objective: Traumatic optic neuropathy can be treated by various methods including steroids and surgical decompression. Endoscopic optic nerve decompression has been suggested to be effective in treating this condition. The aim of this study was to assess the outcome of treating traumatic optic neuropathy with steroids and endoscopic surgical decompression.

Methods: Two hundred and thirty-seven patients with traumatic optic neuropathy were treated with steroids; 176 also consented to endoscopic optic nerve decompression.

Results: The total vision improvement rate was 55 per cent in the 176 patients treated with both steroids and endoscopic optic nerve decompression, compared with 51 per cent in the 61 patients treated with steroids alone; this difference was not statistically significant (p > 0.05). Treatment with steroids plus endoscopic optic nerve decompression resulted in a significantly greater vision improvement in patients with gradual vision loss, compared with those with immediate blindness (68 vs 42 per cent, respectively). Early surgery (within one week) was an important prognostic factor for vision recovery, compared with more delayed surgical treatment (associated vision improvement rates were 60 and 31 per cent, respectively).

Conclusions: Endoscopic optic nerve decompression is a minimally invasive, safe and efficient treatment for traumatic optic neuropathy. Used in combination with steroids, it provides effective rescue for some patients suffering visual loss. It should be undertaken as soon as possible.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Decompression, Surgical / methods*
  • Dexamethasone / therapeutic use*
  • Endoscopy / methods
  • Female
  • Follow-Up Studies
  • Glucocorticoids / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Optic Nerve Injuries / drug therapy*
  • Optic Nerve Injuries / surgery*
  • Orbit / surgery
  • Risk Assessment
  • Treatment Outcome
  • Visual Acuity / drug effects
  • Young Adult

Substances

  • Glucocorticoids
  • Dexamethasone