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[Progress of researches on drug-loaded nanoparticles].

[Article in Chinese]

Author information

  • 1Engineering Research Center for Biomedical Materials under Ministry of Education, East China University of Science and Technology, Shanghai 200237, China.

Abstract

The progress of researches on drug-loaded nanoparticles was summarized in this review. The major emphasis was laid on the selection of wall polymers, technology of preparation, surface modification, investigation of release in vitro and biocompatibility evaluation. Additionally, we envisioned a perspective regarding the development in this field. With the development of synthesis of biodegradable polymer, with the appearance of novel equipment, and with the deep-going studies on modification of nanoparticles surface method, on fabrication of nanoparticles art as well as on evaluation of drug release and reaction between drug and organ, further researches in this field will open up the way to applications of drug-loaded nanoparticles in larger field.

PMID:
18435295
[PubMed - indexed for MEDLINE]
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