Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Curr Protoc Hum Genet. 2008 Apr;Chapter 10:Unit 10.11. doi: 10.1002/0471142905.hg1011s57.

The Catalogue of Somatic Mutations in Cancer (COSMIC).

Author information

  • 1Wellcome Trust Genome Campus, Hinxton, United Kingdom.

Abstract

COSMIC is currently the most comprehensive global resource for information on somatic mutations in human cancer, combining curation of the scientific literature with tumor resequencing data from the Cancer Genome Project at the Sanger Institute, U.K. Almost 4800 genes and 250000 tumors have been examined, resulting in over 50000 mutations available for investigation. This information can be accessed in a number of ways, the most convenient being the Web-based system which allows detailed data mining, presenting the results in easily interpretable formats. This unit describes the graphical system in detail, elaborating an example walkthrough and the many ways that the resulting information can be thoroughly investigated by combining data, respecializing the query, or viewing the results in different ways. Alternate protocols overview the available precompiled data files available for download.

Copyright 2008 by John Wiley & Sons, Inc.

PMID:
18428421
[PubMed - indexed for MEDLINE]
PMCID:
PMC2705836
Free PMC Article

Images from this publication.See all images (16)Free text

Figure 10.11.1
Figure 10.11.2
Figure 10.11.3
Figure 10.11.4
Figure 10.11.5
Figure 10.11.6
Figure 10.11.7
Figure 10.11.8
Figure 10.11.9
Figure 10.11.10
Figure 10.11.11
Figure 10.11.12
Figure 10.11.13
Figure 10.11.14
Figure 10.11.15
Figure 10.11.16
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for John Wiley & Sons, Inc. Icon for PubMed Central
    Loading ...
    Write to the Help Desk