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Arch Dermatol. 2008 Apr;144(4):469-74. doi: 10.1001/archderm.144.4.469.

Utility of lesion diameter in the clinical diagnosis of cutaneous melanoma.

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  • 1Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 550 First Ave, Room H-100, New York, NY 10016, USA.

Abstract

OBJECTIVE:

To determine the utility of the current diameter criterion of larger than 6 mm of the ABCDE acronym for the early diagnosis of cutaneous melanoma.

DESIGN:

Cohort study.

SETTING:

Dermatology hospital-based clinics and community practice offices. Patients A total of 1323 patients undergoing skin biopsies of 1657 pigmented lesions suggestive of melanoma.

MAIN OUTCOME MEASURE:

The maximum lesion dimension (diameter) of each skin lesion was calculated before biopsy using a novel computerized skin imaging system.

RESULTS:

Of 1657 biopsied lesions, 853 (51.5%) were 6 mm or smaller in diameter. Invasive melanomas were diagnosed in 13 of 853 lesions (1.5%) that were 6 mm or smaller in diameter and in 41 of 804 lesions (5.1%) that were larger than 6 mm in diameter. In situ melanomas were diagnosed in 22 of 853 lesions (2.6%) that were 6 mm or smaller in diameter and in 62 of 804 lesions (7.7%) that were larger than 6 mm in diameter. Conclusion The diameter guideline of larger than 6 mm provides a useful parameter for physicians and should continue to be used in combination with the A, B, C, and E criteria previously established in the selection of atypical lesions for skin biopsy.

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PMID:
18427040
[PubMed - indexed for MEDLINE]
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